Role of guinea-pig sperm autoantigens in sperm binding to the zona pellucida and oocyte penetration
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چکیده
منابع مشابه
Sperm Penetration of the Zona Pellucida of the Pig Egg.
In most mammals that have been studied, the first spermatozoon which penetrates an egg stimulates the egg to undergo a reaction—the 'zona reaction'—which bars further spermatozoa from penetrating through the zona pellucida (Braden, Austin & David, 1954). The sequel to the zona reaction may be classified into two categories, according to species: species in which spermatozoa are entirely prevent...
متن کاملA role for the migrating sperm surface antigen PH-20 in guinea pig sperm binding to the egg zona pellucida
After the acrosome reaction, the PH-20 surface antigen of guinea pig sperm migrates from its original location on the posterior head surface to a new location on the inner acrosomal membrane (Myles, D.G., and P. Primakoff, 1984, J. Cell Biol., 99:1634-1641). We have isolated three monoclonal antibodies (MAbs) of the IgG1 subclass, PH-20, PH-21, and PH-22, that bind to the PH-20 antigen. The PH-...
متن کاملRole of sialic acid in bovine sperm-zona pellucida binding.
Sperm binding activity has been detected in zona pellucida (ZP) glycoproteins and it is generally accepted that this activity resides in the carbohydrate moieties. In the present study we aim to identify some of the specific carbohydrate molecules involved in the bovine sperm-ZP interaction. We performed sperm binding competition assays, in vitro fecundation (IVF) in combination with different ...
متن کاملA Role for Mouse Sperm Binding to Sperm Surface Galactosyltransferase the Egg Zona Pellucida in
Past studies have suggested that mouse sperm surface galactosyltransferase may participate during fertilization by binding N-acetylglucosamine (GIcNAc) residues in the zona pellucida. In this paper, we examined further the role of sperm surface galactosyltransferase in mouse fertilization. Two reagents that specifically perturb sperm surface galactosyltransferase activity both inhibit sperm-zon...
متن کاملA role for mouse sperm surface galactosyltransferase in sperm binding to the egg zona pellucida
Past studies have suggested that mouse sperm surface galactosyltransferase may participate during fertilization by binding N-acetylglucosamine (GlcNAc) residues in the zona pellucida. In this paper, we examined further the role of sperm surface galactosyltransferase in mouse fertilization. Two reagents that specifically perturb sperm surface galactosyltransferase activity both inhibit sperm-zon...
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ژورنال
عنوان ژورنال: Reproduction
سال: 1986
ISSN: 1470-1626,1741-7899
DOI: 10.1530/jrf.0.0770347